Your shopping cart is currently empty.
- CRISPR-Cas9
- Cell Culture and Transfection Reagents
- EliteTrust Human Gene ORF Virus Particle Collection
- Featured Products
- Lentiviral Cloning Vectors
- Lentivirus Concentration and Purification kit
- Lentivirus Freeze-Thaw Protection Medium
- Lentivirus Packaging System
- Lentivirus Titration
- Premade Lentivirus
- Premade shRNA Lentivirus
- Premade shRNA Lentivitus
- Premade Stable Cell Line
- Stem Cell Research
- Vectors for iPS Cells Generation
- xpath of 1st category mapping
- xpath of 2nd category mapping
- DNA Mutagenesis
- EliteTrust Cell Authentication Service
- EliteTrust Custom Adeno-Associated Virus Production
- EliteTrust Custom Gene Targeting Service
- EliteTrust Custom Lentivirus Production
- EliteTrust Custom Retrovirus Production Service
- EliteTrust Custom Stable Cell Line Generation Service
- EliteTrust Stable Cell Line Mycoplasma Detection Service
- xpath of 1st department mapping
- xpath of 2nd department mapping
PDP1 Full-Length ORF: Human Gene Retrovirus
Gene ID: 54704
Synonym(s): PDH, PDP, PDPC, PPM2A, PPM2C
Description: Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009].This ORF sequence encodes a protein that is exactly the same as the proteins of NM_001161781, NM_018444. The protein has a functional site and/or region.
Catalog Number | Product | Size | Price | Qty |
---|---|---|---|---|
ET-101462-RV-50
|
PDP1 Retrovirus Particles (MSCV, PuroR)
|
2x25 ul per vial, 1x10^8 TU/ml |
Price:
$700.00
|
|
ET-101462-RV-200
|
PDP1 Retrovirus Particles (MSCV, PuroR)
|
8x25 ul per vial, 1x10^8 TU/ml |
Price:
$1,200.00
|
|
ET-101462-RV-pd
|
PDP1 Retrovirus Transfer Vector (MSCV, PuroR): Glycerol Stock
|
1 vial |
Price:
$1,200.00
|