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SENP6 Full-Length ORF: Human Gene GFP Lentivirus
Gene ID: 26054
Synonym(s): SSP1, SUSP1
Description: Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000 [PubMed 10799485]). SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009].This ORF sequence encodes a protein that is exactly the same as the protein of NM_001100409. The protein has 14 functional sites and/or regions.
Catalog Number | Product | Size | Price | Qty |
---|---|---|---|---|
ET-100925-LVG-50
|
SENP6 Lentivirus Particles (BlastR, GFP)
|
2x25 ul per vial, 1x10^8 TU/ml |
Price:
$700.00
|
|
ET-100925-LVG-200
|
SENP6 Lentivirus Particles (BlastR, GFP)
|
8x25 ul per vial, 1x10^8 TU/ml |
Price:
$1,200.00
|
|
ET-100925-LVG-pd
|
SENP6 Lentiviral Transfer Vector (BlastR, GFP): Glycerol stock
|
1 vial |
Price:
$1,200.00
|