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CTSL Full-Length ORF: Human Gene Retrovirus
Gene ID: 1514
Synonym(s): CATL, CTSL1, MEP
Description: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Additionally, this protein cleaves the S1 subunit of the SARS-CoV-2 spike protein, which is necessary for entry of the virus into the cell. [provided by RefSeq, Aug 2020].This clone has a DNA sequence that is of length 1042bp. Its ORF sequence is of length 1002bp. This ORF encodes a protein that embeds the full-length protein of NM_001257973. For more detailed information regarding this clone and its ORF, please contact [email protected].
Catalog Number | Product | Size | Price | Qty |
---|---|---|---|---|
ET-110806-RV-50
|
CTSL Retrovirus Particles (MSCV, PuroR)
|
2x25 ul per vial, 1x10^8 TU/ml |
Price:
$700.00
|
|
ET-110806-RV-200
|
CTSL Retrovirus Particles (MSCV, PuroR)
|
8x25 ul per vial, 1x10^8 TU/ml |
Price:
$1,200.00
|
|
ET-110806-RV-pd
|
CTSL Retrovirus Transfer Vector (MSCV, PuroR): Glycerol Stock
|
1 vial |
Price:
$1,200.00
|