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PFKFB4 Full-Length ORF: Human Gene Retrovirus
Gene ID: 5210
Description: The protein encoded by this gene is one of four bifunctional kinase/phosphatases that regulate the concentration of the glycolytic byproduct fructose-2,6-bisphosphate (F2,6BP). The encoded protein is highly expressed in cancer cells and is induced by hypoxia. This protein is essential to the survival of cancer cells under conditions of hypoxia, because it increases the amount of F2,6BP and ATP at a time when the cell cannot produce much of them. This finding suggests that this protein may be a good target for disruption in cancer cells, hopefully imperiling their survival. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015].This clone has a DNA sequence that is of length 1450bp. Its ORF sequence is of length 1410bp. This ORF encodes a protein that embeds the full-length protein of NM_001317138. For more detailed information regarding this clone and its ORF, please contact [email protected].
Catalog Number | Product | Size | Price | Qty |
---|---|---|---|---|
ET-110736-RV-50
|
PFKFB4 Retrovirus Particles (MSCV, PuroR)
|
2x25 ul per vial, 1x10^8 TU/ml |
Price:
$700.00
|
|
ET-110736-RV-200
|
PFKFB4 Retrovirus Particles (MSCV, PuroR)
|
8x25 ul per vial, 1x10^8 TU/ml |
Price:
$1,200.00
|
|
ET-110736-RV-pd
|
PFKFB4 Retrovirus Transfer Vector (MSCV, PuroR): Glycerol Stock
|
1 vial |
Price:
$1,200.00
|