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- CRISPR-Cas9
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INS Full-Length ORF: Human Gene GFP Lentivirus
Gene ID: 3630
Synonym(s): IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10, PNDM4
Description: This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq, May 2020].This ORF sequence encodes a protein that is exactly the same as the proteins of NM_001291897, NM_001185097, NM_001185098, NM_000207.
Catalog Number | Product | Size | Price | Qty |
---|---|---|---|---|
ET-107930-LVG-50
|
INS Lentivirus Particles (BlastR, GFP)
|
2x25 ul per vial, 1x10^8 TU/ml |
Price:
$700.00
|
|
ET-107930-LVG-200
|
INS Lentivirus Particles (BlastR, GFP)
|
8x25 ul per vial, 1x10^8 TU/ml |
Price:
$1,200.00
|
|
ET-107930-LVG-pd
|
INS Lentiviral Transfer Vector (BlastR, GFP): Glycerol stock
|
1 vial |
Price:
$1,200.00
|