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SPAM1 Full-Length ORF: Human Gene GFP Lentivirus
Gene ID: 6677
Synonym(s): HEL-S-96n, HYA1, HYAL1, HYAL3, HYAL5, PH-20, PH20, SPAG15
Description: Hyaluronidase degrades hyaluronic acid, a major structural proteoglycan found in extracellular matrices and basement membranes. Six members of the hyaluronidase family are clustered into two tightly linked groups on chromosome 3p21.3 and 7q31.3. This gene was previously referred to as HYAL1 and HYA1 and has since been assigned the official symbol SPAM1; another family member on chromosome 3p21.3 has been assigned HYAL1. This gene encodes a GPI-anchored enzyme located on the human sperm surface and inner acrosomal membrane. This multifunctional protein is a hyaluronidase that enables sperm to penetrate through the hyaluronic acid-rich cumulus cell layer surrounding the oocyte, a receptor that plays a role in hyaluronic acid induced cell signaling, and a receptor that is involved in sperm-zona pellucida adhesion. Abnormal expression of this gene in tumors has implicated this protein in degradation of basement membranes leading to tumor invasion and metastasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].This ORF sequence encodes a protein that is exactly the same as the protein of NM_003117. The protein has 6 functional sites and/or regions.
Catalog Number | Product | Size | Price | Qty |
---|---|---|---|---|
ET-105290-LVG-50
|
SPAM1 Lentivirus Particles (BlastR, GFP)
|
2x25 ul per vial, 1x10^8 TU/ml |
Price:
$700.00
|
|
ET-105290-LVG-200
|
SPAM1 Lentivirus Particles (BlastR, GFP)
|
8x25 ul per vial, 1x10^8 TU/ml |
Price:
$1,200.00
|
|
ET-105290-LVG-pd
|
SPAM1 Lentiviral Transfer Vector (BlastR, GFP): Glycerol stock
|
1 vial |
Price:
$1,200.00
|