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CCL5 Full-Length ORF: Human Gene Retrovirus
Gene ID: 6352
Synonym(s): D17S136E, eoCP, RANTES, SCYA5, SIS-delta, SISd, TCP228
Description: This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013].This ORF sequence encodes a protein that is exactly the same as the protein of NM_002985. The protein has 3 functional sites and/or regions.
Catalog Number | Product | Size | Price | Qty |
---|---|---|---|---|
ET-105212-RV-50
|
CCL5 Retrovirus Particles (MSCV, PuroR)
|
2x25 ul per vial, 1x10^8 TU/ml |
Price:
$700.00
|
|
ET-105212-RV-200
|
CCL5 Retrovirus Particles (MSCV, PuroR)
|
8x25 ul per vial, 1x10^8 TU/ml |
Price:
$1,200.00
|
|
ET-105212-RV-pd
|
CCL5 Retrovirus Transfer Vector (MSCV, PuroR): Glycerol Stock
|
1 vial |
Price:
$1,200.00
|