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USP18 Full-Length ORF: Human Gene GFP Lentivirus
Gene ID: 11274
Synonym(s): ISG43, PTORCH2, UBP43
Description: The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011].This ORF sequence encodes a protein that is exactly the same as the protein of NM_017414. The protein has 5 functional sites and/or regions.
Catalog Number | Product | Size | Price | Qty |
---|---|---|---|---|
ET-104549-LVG-50
|
USP18 Lentivirus Particles (BlastR, GFP)
|
2x25 ul per vial, 1x10^8 TU/ml |
Price:
$700.00
|
|
ET-104549-LVG-200
|
USP18 Lentivirus Particles (BlastR, GFP)
|
8x25 ul per vial, 1x10^8 TU/ml |
Price:
$1,200.00
|
|
ET-104549-LVG-pd
|
USP18 Lentiviral Transfer Vector (BlastR, GFP): Glycerol stock
|
1 vial |
Price:
$1,200.00
|