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PICALM Full-Length ORF: Human Gene Retrovirus
Gene ID: 8301
Synonym(s): CALM, CLTH, LAP
Description: This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10;11)(p13;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011].This ORF sequence encodes a protein that is exactly the same as the protein of NM_001008660.
Catalog Number | Product | Size | Price | Qty |
---|---|---|---|---|
ET-102815-RV-50
|
PICALM Retrovirus Particles (MSCV, PuroR)
|
2x25 ul per vial, 1x10^8 TU/ml |
Price:
$700.00
|
|
ET-102815-RV-200
|
PICALM Retrovirus Particles (MSCV, PuroR)
|
8x25 ul per vial, 1x10^8 TU/ml |
Price:
$1,200.00
|
|
ET-102815-RV-pd
|
PICALM Retrovirus Transfer Vector (MSCV, PuroR): Glycerol Stock
|
1 vial |
Price:
$1,200.00
|