Your shopping cart is currently empty.
- CRISPR-Cas9
- Cell Culture and Transfection Reagents
- EliteTrust Human Gene ORF Virus Particle Collection
- Featured Products
- Lentiviral Cloning Vectors
- Lentivirus Concentration and Purification kit
- Lentivirus Freeze-Thaw Protection Medium
- Lentivirus Packaging System
- Lentivirus Titration
- Premade Lentivirus
- Premade shRNA Lentivirus
- Premade shRNA Lentivitus
- Premade Stable Cell Line
- Stem Cell Research
- Vectors for iPS Cells Generation
- xpath of 1st category mapping
- xpath of 2nd category mapping
- DNA Mutagenesis
- EliteTrust Cell Authentication Service
- EliteTrust Custom Adeno-Associated Virus Production
- EliteTrust Custom Gene Targeting Service
- EliteTrust Custom Lentivirus Production
- EliteTrust Custom Retrovirus Production Service
- EliteTrust Custom Stable Cell Line Generation Service
- EliteTrust Stable Cell Line Mycoplasma Detection Service
- xpath of 1st department mapping
- xpath of 2nd department mapping
SDHB Full-Length ORF: Human Gene GFP Lentivirus
Gene ID: 6390
Synonym(s): CWS2, IP, MC2DN4, PGL4, PPGL4, SDH, SDH1, SDH2, SDHIP
Description: This tumor suppressor gene encodes the iron-sulfur protein subunit of the succinate dehydrogenase (SDH) enzyme complex which plays a critical role in mitochondria. The SDH enzyme complex is composed of four nuclear-encoded subunits. This enzyme complex converts succinate to fumarate which releases electrons as part of the citric acid cycle, and the enzyme complex additionally provides an attachment site for released electrons to be transferred to the oxidative phosphorylation pathway. The SDH enzyme complex plays a role in oxygen-related gene regulation through its conversion of succinate, which is an oxygen sensor that stabilizes the hypoxia-inducible factor 1 (HIF1) transcription factor. Sporadic and familial mutations in this gene result in paragangliomas, pheochromocytoma, and gastrointestinal stromal tumors, supporting a link between mitochondrial dysfunction and tumorigenesis. Mutations in this gene are also implicated in nuclear type 4 mitochondrial complex II deficiency. [provided by RefSeq, Jun 2022].This ORF sequence encodes a protein that is exactly the same as the protein of NM_003000. The protein has 3 functional sites and/or regions.
Catalog Number | Product | Size | Price | Qty |
---|---|---|---|---|
ET-101691-LVG-50
|
SDHB Lentivirus Particles (BlastR, GFP)
|
2x25 ul per vial, 1x10^8 TU/ml |
Price:
$700.00
|
|
ET-101691-LVG-200
|
SDHB Lentivirus Particles (BlastR, GFP)
|
8x25 ul per vial, 1x10^8 TU/ml |
Price:
$1,200.00
|
|
ET-101691-LVG-pd
|
SDHB Lentiviral Transfer Vector (BlastR, GFP): Glycerol stock
|
1 vial |
Price:
$1,200.00
|