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TNFRSF1B Full-Length ORF: Human Gene Retrovirus
Gene ID: 7133
Synonym(s): CD120b, p75, p75TNFR, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80
Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008].This ORF sequence encodes a protein that is exactly the same as the protein of NM_001066. The protein has 15 functional sites and/or regions.
Catalog Number | Product | Size | Price | Qty |
---|---|---|---|---|
ET-101571-RV-50
|
TNFRSF1B Retrovirus Particles (MSCV, PuroR)
|
2x25 ul per vial, 1x10^8 TU/ml |
Price:
$700.00
|
|
ET-101571-RV-200
|
TNFRSF1B Retrovirus Particles (MSCV, PuroR)
|
8x25 ul per vial, 1x10^8 TU/ml |
Price:
$1,200.00
|
|
ET-101571-RV-pd
|
TNFRSF1B Retrovirus Transfer Vector (MSCV, PuroR): Glycerol Stock
|
1 vial |
Price:
$1,200.00
|